Table 2.

α-glucosidase activity of methanolic extract of Cornus capitata and its fractions

Plant extract/Fractionate	Percentage α-glucosidase inhibition						IC 50 (μg/mL)
	12.5 μg/mL	25 μg/mL	50 μg/mL	100 μg/mL	200 μg/mL	400 μg/mL
Cornus capitata (Leaves)	63.68 ± 1.98a	97.81 ± 0.03a	98.37 ± 0.12a	97.43 ± 0.18a	97.18 ± 0.18	94.70 ± 0.41	12.5
Hexane Fraction	2.78 ± 2.73b	16.04 ± 4.78b	31.94 ± 5.17b	69.07 ± 2.51a	98.98 ± 1.22	96.52 ± 3.02	65.12
Diethyl ether Fraction	8.31 ± 0.87b	13.04 ± 2.80b	30.98 ± 4.21b	52.64 ± 6.11a	96.54 ± 0.92	95.65 ± 0.65	71.85
Ethyl acetate Fraction	14.60 ± 3.07bc	18.42 ± 2.65b	50.06 ± 0.36bc	84.45 ± 2.80a	98.55 ± 0.51	97.45 ± 1.08	50
n-Butanol Fraction	10.57 ± 0.21bc	14.93 ± 2.83b	26.07 ± 4.53bc	78.75 ± 4.63ab	98.35 ± 0.24	97.75 ± 0.43	61.175

Values are mean ± S.E. of three parallel measurements

Different letters indicate significant differences between same concentrations of Cornus capitata methanolic extract and its fractionates (p < 0.05, Tukeys HSD test, F-ratio- 49.935 (12.5 μg/mL), 55.279 (25 μg/mL), 46.702 (50 μg/mL), 16.690 (100 μg/mL), 1.861 (200 μg/mL), 0.683 (400 μg/mL)

Cornus capitata methanolic extract (leaves) (4.25% at 1.5 μg/mL; 6% at 3.1 μg/mL and 19% inhibition at 6.25 μg/mL concentration)