TABLE 2.
The 5-Year Prevalence and Incidence Rates of Children With MCCs Living in Olmsted County, Minnesota, During the Study Period (1999–2014)
| Prevalence at Each Time Pointa (95% CI) | Incidence at Each Time Pointa (95% CI) | |||||
|---|---|---|---|---|---|---|
| 2004 | 2009 | 2014 | 1999 | 2004 | 2009 | |
| Overall | 1237 (1119–1364) | 1448 (1321–1584) | 1961 (1813–2118) | 250 (223–280) | 273 (245–304) | 333 (310–366) |
| Age, y | ||||||
| <1 | 893 (529–1411) | 1437 (970–2052) | 1259 (815–1859) | 491 (134–1256) | 1306 (675–2282) | 315 (65–920) |
| 1–4 | 1649 (1358–1971) | 1858 (1578–2174) | 2441 (2107–2813) | 231 (166–313) | 150 (101–214) | 303 (235–385) |
| 5–9 | 1057 (850–1299) | 1196 (980–1446) | 1798 (1542–2084) | 115 (83–155) | 144 (108–187) | 213 (172–262) |
| 10–17 | 1183 (1014–1373) | 1361 (1172–1573) | 1904 (1678–2152) | 330 (287–377) | 375 (329–425) | 426 (376–481) |
| Age-adjusted rate | 1235 (1114–1356) | 1429 (1300–1558) | 1958 (1807–2110) | 258 (221–295) | 312 (264–359) | 335 (299–371) |
| Sex | ||||||
| Boys | 1355 (1184–1544) | 1534 (1353–1733) | 2119 (1905–2349) | 240 (203–282) | 270 (231–314) | 333 (289–380) |
| Girls | 1113 (955–1290) | 1358 (1183–1550) | 1794 (1594–2014) | 260 (221–305) | 277 (236–322) | 333 (289–381) |
| Sex-adjusted rate | 1237 (1116–1358) | 1448 (1318–1578) | 1960 (1809–2111) | 250 (222–278) | 273 (244–303) | 333 (301–364) |
| Ethnicity | ||||||
| Non-Hispanic white | 1264 (1126–1414) | 1415 (1267–1576) | 1933 (1755–2126) | 253 (222–287) | 287 (254–323) | 334 (297–374) |
| Other | 1160 (941–1416) | 1529 (1291–1798) | 2016 (1759–2300) | 238 (180–308) | 229 (177–291) | 329 (272–395) |
| Ethnicity-adjusted rate | 1216 (1085–1347) | 1468 (1327–1609) | 1972 (1814–2129) | 246 (213–279) | 260 (229–292) | 332 (297–366) |
| Age-, sex-, and race-adjusted rate | 1200 (1070–1329) | 1436 (1297–1576) | 1948 (1792–2104) | 256 (213–298) | 300 (250–350) | 335 (296–373) |
MCCs were defined as ≥2 CCCs by using the pediatric CCCs classification system version 2.
a
Prevalence and incidence rates per 100 000 person-y (based on a 5-y capture frame) were calculated by using the population-based cohort at each time period (2004, 2009, and 2014 for prevalence; 1999, 2004, and 2009 for incidence).