TABLE 3.
Association of HOUSES With Prevalence and Incidence Rates of Children With MCCs
| Prevalence at Each Time Pointa (95% CI) | Incidence at Each Time Pointa (95% CI) | |||||
|---|---|---|---|---|---|---|
| 2004 | 2009 | 2014 | 1999 | 2004 | 2009 | |
| HOUSESb | ||||||
| First quartile | 1443 (1173–1756) | 1576 (1289–1908) | 2225 (1870–2627) | 262 (202–334) | 273 (214–343) | 363 (293–445) |
| Second quartile | 1435 (1166–1747) | 1587 (1303–1914) | 2327 (1967–2734) | 237 (181–305) | 290 (230–362) | 278 (219–349) |
| Third quartile | 1134 (898–1413) | 1563 (1281–1889) | 2339 (1980–2745) | 305 (241–380) | 304 (243–377) | 346 (279–425) |
| Fourth quartile | 1124 (890–1400) | 1462 (1191–1776) | 1663 (1364–2007) | 224 (170–288) | 267 (130–283) | 362 (294–442) |
| Pc | .039 | .583 | .038 | .726 | .982 | .655 |
MCCs were defined as ≥2 CCCs by using the pediatric CCCs classification system version 2.
a
Prevalence and incidence rates per 100 000 person-y (based on 5-y capture frame) were calculated using the population-based cohort at each time period (2004, 2009, and 2014 for prevalence; 1999, 2004, and 2009 for incidence).
b
The first quartile is the lowest quartile, and the fourth quartile is the highest quartile.
c
The P value is used to test the linear trend of HOUSES quartiles with prevalence and incidence rates within each period.