Figure 3.

Weight changes. Body weight (as a percentage of baseline) increased over time in all groups and reached a similar value at 30 months. However, ImE delayed the rate of increase until 12 to 18 months, after which time both groups exhibited similar weights. Administration of DE had no effect on body weight. Data are average fold changes of individual results normalized by starting value ± SEM. *Groups are different by two-way ANOVA. At the 6-month time point, the placebo group is different from the ImE group by Sidak post hoc pairwise comparison.