Figure 4.

Changes in body composition as measured by DEXA scan. (A) Total fat mass increased with time up to 18 months then stabilized for the remainder of the study. (B) Lean mass decreased with time up to 18 months, then stabilized for the remainder of the study. (C) Truncal fat increased with time up to 18 months, then stabilized for the remainder of the study. There were no statistical differences between the treatment groups in any of the measures at any of the study time points. Data are average fold change of individual results normalized by starting value ± SEM. ^†There was a significant difference across time with two-way ANOVA.