Figure 5.

Cell elongation and tissue length regulation. A. Epithelial cell elongation is illustrated in the wild-type and Celar1 mutant situations. In the wild-type, the cells are intrinsically elongated along the longitudinal direction of the tube. Cell-cell junctional tensions are almost similar between the two genotypes (red lines). Combination of the elongated shapes of the cells and the cell-cell junctional tensions results in increased epithelial tension in the wild-type compared to that in the mutant (black and gray arrows). B. Outcomes of intrinsic cell elongation are explained. In the absence of junctional remodeling, the tissue is also elongated. By contrast, in the presence of junctional remodeling, the tissue can be shrunk.