Table 2.
Texture parameter | Fibrosis stage | Threshold | Sensitivity | Specificity | AUC | Lower CI | Upper CI |
Mean (ssf 3) | F0 vs F1-F4 | 0.3 | 0.78 | 0.73 | 0.81 | 0.77 | 0.85 |
F0-1 vs F2-4 | 0.44 | 0.74 | 0.75 | 0.80 | 0.76 | 0.83 | |
F0-2 vs F3-4 | 0.54 | 0.78 | 0.73 | 0.82 | 0.79 | 0.86 | |
F0-3 vs F4 | 0.9 | 0.75 | 0.81 | 0.85 | 0.82 | 0.88 | |
Mpp | F0 vs F1-F4 | 98.4 | 0.3 | 0.9 | 0.58 | 053 | 0.63 |
F0-1 vs F2-4 | 100.3 | 0.35 | 0.87 | 0.62 | 0.58 | 0.67 | |
F0-2 vs F3-4 | 107.2 | 0.55 | 0.76 | 0.67 | 0.63 | 0.72 | |
F0-3 vs F4 | 106.4 | 0.54 | 0.71 | 0.63 | 0.58 | 0.68 | |
Skewness | F0 vs F1-F4 | 1.5 | 0.64 | 0.71 | 0.69 | 0.64 | 0.74 |
F0-1 vs F2-4 | 1.6 | 0.74 | 0.66 | 0.73 | 0.68 | 0.77 | |
F0-2 vs F3-4 | 1.4 | 0.76 | 0.68 | 0.76 | 0.71 | 0.80 | |
F0-3 vs F4 | 1.4 | 0.85 | 0.63 | 0.78 | 0.75 | 0.82 | |
Kurtosis | F0 vs F1-F4 | 4.5 | 0.4 | 0.87 | 0.61 | 0.56 | 0.65 |
F0-1 vs F2-4 | 5.7 | 0.54 | 0.79 | 0.65 | 0.60 | 0.69 | |
F0-2 vs F3-4 | 4.6 | 0.51 | 0.82 | 0.66 | 0.61 | 0.70 | |
F0-3 vs F4 | 4.6 | 0.61 | 0.79 | 0.71 | 0.66 | 0.76 |
AUC, area under the curve; CI, confidence interval;
All measurements were performed in the portal venous phase in segments IV-VIII. Mean at spatial scaling factor 3 (medium filter), mpp at ssf 0, skewness and kurtosis at ssf 6 (coarse filter).