Figure 2.

Effect of a meal on average activation across a priori appetite-processing regions. (A–C) Mean parameter estimates across a priori regions in children of HW and children with OB were measured before (filled/open bars) and after (striped bars) a standardized test meal for the contrasts of (A) high-calorie foods vs objects, (B) low-calorie foods vs objects, and (C) high-calorie vs low-calorie foods. Data are means ± SEM. P values were determined by linear mixed models. *P < 0.05, **P < 0.0001, vs premeal within same group; ^†P < 0.05, HW group vs OB group.