Table 1.
Summary of demographic, cognitive, genetic and lifestyle-related health information for men and women.
| Mean (SD) | Men (n = 72) | Women (n = 94) | Statistic (p-value) |
|---|---|---|---|
| Age (in years) | 56 (8.3) | 55.6 (8.2) | ns |
| Years of education | 16.6 (3.4) | 16.5 (3.3) | ns |
| NART | 116.9 (6.4) | 116.6 (6.9) | ns |
| MMSE | 29 (1.0) | 29.2 (0.9) | ns |
| Positive Family History dementia | 36.1 | 35.1% | ns |
| APOE Genotype | 44.4% ε4+, 55.6% ε4- | 34.4% ε4+, 65.6% ε4- | ns |
| Central obesity (Waist Hip Ratio) | 84.7% | 44.7% | χ2(1) = 28.34 (<0.0001) |
| Overweight/Obese (BMI) | 50%/18% | 39.4%/21.3% | ns |
| Subcutaneous fat area fraction | 0.35 (0.1) | 0.41 (0.1) | t(128) = 3.5 (0.001) |
| Visceral fat area fraction | 0.22 (0.06) | 0.19 (0.06) | t(128) = 3.8 (0.002) |
| Systolic Hypertension | 36.1% | 22.3% | ns |
| Smokers | 4.2% | 6.4% | ns |
| Diabetes | 2.8% | 1.1% | ns |
| Statins | 13.9% | 3.3% | χ2(1) = 6.5 (0.01) |
| Alcohol units per week | 11.5 (11.9) | 4.3 (5.0) | t(156) = 5.2 (<0.0001) |
| Physical activities (Median hours per week) | 11.9 (12.7) | 9.2 (11.5) | ns |
| Adiponectin log10 ng/ml | 3.9 (0.26) | 4.1 (0.22) | t(146) = 4.64 (<0.0001) |
| Leptin log10 pg/ml | 3.7 (0.39) | 4.3 (0.37) | t(146) = 9.02 (<0.0001) |
| C-Reactive Protein log10 ng/ml | 3.0 (0.45) | 3.1 (0.49) | ns |
| Interleukin-8 log10 pg/ml | 0.7 (0.14) | 0.7 (0.16) | ns |
Abbreviations: APOE = Apolipoprotein E, BMI = Body Mass Index, MMSE = Mini Mental State Examination, NART = National Adult Reading Test.