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. 2019 Apr 1;189:793–803. doi: 10.1016/j.neuroimage.2019.02.007

Table 3.

Rotated component matrix of the principal component analysis of the white matter microstructural indicesa.

ROI WM index Components
ISOSF/ODI kf MPF ICSF Fornix
Fornix ICSF −0.201 −0.039 −0.081 0.497 0.431
ISOSF −0.045 0.012 −0.015 0.039 −0.93
ODI 0.622 −0.041 −0.027 −0.122 −0.364
MPF −0.114 0.041 0.458 0.049 0.782
kf −0.09 0.525 −0.014 0.008 0.757
Left PHC ICSF 0.264 0.107 0.101 0.792 −0.191
ISOSF 0.781 −0.045 0.01 0.11 −0.042
ODI 0.641 −0.251 −0.091 −0.287 0.123
MPF 0.124 0.276 0.552 0.347 0.005
kf 0.09 0.814 −0.048 0.18 −0.004
Right PHC ICSF 0.116 0.054 0.225 0.77 −0.233
ISOSF 0.752 −0.008 0.09 −0.08 −0.081
ODI 0.621 −0.086 −0.155 −0.285 0.206
MPF 0.049 0.149 0.701 0.265 −0.01
kf 0.007 0.82 0.026 0.156 0.107
Left UF ICSF −0.043 0.075 0.377 0.743 0.007
ISOSF 0.728 −0.062 0.234 −0.083 −0.029
ODI 0.831 −0.054 −0.066 −0.103 0.028
MPF 0.018 0.262 0.76 0.182 0.04
kf −0.154 0.814 0.178 0.108 −0.054
Right UF ICSF −0.039 0.09 0.427 0.647 0.089
ISOSF 0.642 −0.021 0.226 −0.28 0.066
ODI 0.781 −0.03 −0.025 −0.154 0.039
MPF −0.027 0.204 0.772 0.086 0.002
kf 0.04 0.752 0.351 0.005 −0.043
Left CST ICSF −0.222 0.02 0.031 0.66 0.085
ISOSF 0.742 −0.087 −0.032 0.077 −0.088
ODI 0.797 0.029 0.022 0.036 0.097
MPF −0.067 −0.045 0.83 0.132 0.042
kf −0.155 0.818 0.107 −0.088 0.073
Right CST ICSF −0.271 0.049 0.147 0.56 0.079
ISOSF 0.716 −0.116 −0.127 0.115 −0.132
ODI 0.826 0.026 −0.053 0.064 0.065
MPF −0.114 −0.024 0.85 0.077 −0.015
kf −0.167 0.802 0.169 −0.067 0.069
Total WM ICSF −0.298 0.001 0.267 0.701 −0.333
ISOSF 0.752 −0.037 −0.105 −0.147 0.201
ODI 0.527 0.06 −0.186 0.005 −0.195
MPF −0.065 0.1 0.812 0.196 0.235
kf −0.095 0.928 0.051 0.047 0.062

Loadings >0.5 are highlighted in bold. Abbreviations: CST = corticospinal tract, ICSF = intracellular signal fraction, ISOSF = isotropic signal fraction, kf = forward exchange rate, MPF = macromolecular proton fraction, ODI = orientation dispersion index, PHC = parahippocampal cingulum, ROI = region of interest, UF = uncinate fasciculus, WM = white matter.

a

Rotation method: Varimax with Kaiser normalization.