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. 2019 Mar 22;13:941–948. doi: 10.2147/DDDT.S188171

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© 2019 Teare et al. This work is published and licensed by Dove Medical Press Limited

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Chromatograms of the N-linked glycan charge separations for (A) rAHF-PFM; (B) rFVIII-FS; and (C) BAY 81–8973.

Notes: Separation of the neutral, mono-, di-, tri-, and tetra-sialylated N glycans are shown in their respective retention time windows. Major glycan structures are annotated.

Abbreviations: LU, luminescence units; rAHF-PFM, antihemophilic factor (recombinant) plasma/albumin-free method; rFVIII-FS, sucrose-formulated recombinant factor VIII.

Chromatograms of the N-linked glycan charge separations for (A) rAHF-PFM; (B) rFVIII-FS; and (C) BAY 81–8973.

Notes: Separation of the neutral, mono-, di-, tri-, and tetra-sialylated N glycans are shown in their respective retention time windows. Major glycan structures are annotated.

Abbreviations: LU, luminescence units; rAHF-PFM, antihemophilic factor (recombinant) plasma/albumin-free method; rFVIII-FS, sucrose-formulated recombinant factor VIII.