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. 2019 Mar 22;13:941–948. doi: 10.2147/DDDT.S188171

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© 2019 Teare et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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FVIII concentration-time curves after single 50 IU/kg dose administration of BAY 81–8973, rFVIII-FS, and rAHF-PFM using the chromogenic assay.17,23

Note: Reprinted by permission from Springer Nature: Springer Nature:Clin Pharmacokinet. Improved pharmacokinetics with Bay 81-8973 versus antihemophilic factor (recombinant) plasma/albumin-free method: a randomized pharmacokinetic study in patients with severe hemophilia A. Shah A, Solms A, Garmann D, et al. 2017;56(9):1045–1055.17 This poster was originally published in Blood 132:1209. Teare et al. Improved Pharmacokinetic Profile for BAY 81-8973. Due to Increased Branching and Sialylation of N-Linked Glycans of Recombinant Factor VIII. Poster presented at: American Society of Hematology; December 1–4; 2018; San Diago, USA. © the American Society of Hematology.23

Abbreviations: FVIII, factor VIII; rAHF-PFM, antihemophilic factor (recombinant) plasma/albumin-free method; rFVIII-FS, sucrose-formulated recombinant factor VIII.