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. 2019 Mar 26;14(3):e0214436. doi: 10.1371/journal.pone.0214436

Table 3. Basic clinical and demographic data of a subgroup of the lifestyle intervention study cohort separated by CHeK alterations during study course (data from T0).

Parameter CHeK decrease CHeK increase
N 23 15
Female / male 15 / 8 (65% / 35%) 12 / 3 (80% / 20%)
Age 42.0 ± 11.0 y 42.3 ± 11.0 y
BMI 42.5 ± 6.9 kg/m2 40.9 ± 5.6 kg/m2
ALT 34.4 ± 17.8 U/l 30.8 ± 20.8
AST 26.4 ± 7.7 U/l 25.3 ± 14.1
GGT 45.5 ± 59.0 U/l 27.2 ± 16.2 U/l
HbA1c 5.6 ± 0.8 5.7 ± 0.6
HDL 54.0 ± 13.5 50.7 ± 16.2
LDL 128.2 ± 43.4 126.5 ± 36.6
Adiponectin 6.4 ± 4.9 8.0 ± 4.8
M30 243.8 ± 271.2 U/l 165.3 ± 91.9
CHeK 3.9 (-2.9–21.4) 0.8 (-3.8–6.8)*
Presence of steatosis in ultrasound 18 (78%) 13 (87%)

*: p vs. patients with CHeK decrease < 0.05