Fig 4.

AVF intervention rates for fish oil versus placebo (A) and aspirin versus placebo (B). Overall interventions: Surgical or radiological revision or dilatation of the AVF from or proximal to the anastomosis to the ipsilateral central vein, dilation of central venous stenosis, ligation of tributaries, superficialisation of AVF, thrombolysis or thrombectomy, ligation of fistula or salvage by distal reconstruction and interval ligation, others. Rescue interventions: Thrombolysis or thrombectomy. Non-rescue interventions: Surgical or radiological revision or dilatation of the AVF from or proximal to the anastomosis to the ipsilateral central vein, dilation of central venous stenosis, ligation of tributaries, superficialisation of AVF, ligation of fistula or salvage by distal reconstruction and interval ligation. Regions included Australia and New Zealand, Malaysia and the United Kingdom. Pre-specified baseline characteristics included planned AVF site (lower arm, upper arm), diabetes mellitus, age group (quartiles), cardiovascular comorbidity, including any one or more of peripheral vascular disease, ischaemic heart disease and cerebrovascular accidents, and renal replacement therapy at baseline (no [pre-dialysis/transplant], yes [haemodialysis or peritoneal dialysis]). ^aAdjusted for differences in aspirin use (no aspirin, randomized to aspirin, open-label aspirin).