Table 4. Multivariate logistic regression clinical model and model with NT-proBNP included for the prediction of primary endpoint (i.e. the two-year prognosis in terms of all-cause mortality, heart transplantation and LVAD implantation).

		Clinical model		Biomarker-clinical model
Predictor		OR (95% CI)	P	OR (95% CI)	P
Age [years]	10-unit increase	1.23 (1.04; 1.46)	0.015	1.18 (0.99; 1.40)	0.065
NT-proBNP [ng/L]	1,000-unit increase	——		1.18 (1.08; 1.29)	< 0.001
NYHA classification	1-unit increase	1.92 (1.36; 2.72)	< 0.001	1.70 (1.19; 2.44)	0.003
Hemoglobin [g/l]	<130 in men, <120 in women	1.94 (1.07; 3.50)	0.028	1.73 (1.12; 2.67)	0.013
Sodium [mmol/l]	< 135 (ref. ≥ 135)	1.94 (1.07; 3.50)	0.028	2.07 (1.12; 3.81)	0.020
Uric acid [μmol/l]	100–unit increase	1.46 (1.20; 1.78)	< 0.001	1.36 (1.11; 1.67)	0.003
Furosemide [mg]	> 40 (ref. ≤ 40)	2.90 (1.94; 4.34)	< 0.001	2.84 (1.87; 4.33)	< 0.001