Fig 1. Demographic and clinical characteristics of French and Romanians with MetS.

Left panel, genetic distances between French and Romanian samples and HapMap populations. PCA was performed on 654,000 SNPs, merged with HapMap data and pruned (R² > 0.8) and eigenvectors were plotted as PC1/PC2. The 95% tolerance ellipse was constructed using the JMP program. YRI, CHB, JPT and CEU stand for Yoruba in Ibadan, Nigeria, Han Chinese in Beijing, Japanese in Tokyo, Utah residents with Northern and Western European ancestry from the CEPH collection, respectively. Right panel, relationship between cumulative criteria for MetS and HOMA_IR index in French and Romanian subjects. The curve represents the variation of the sensitivity index (S_I) obtained in a French population using the minimal model calculation after in vivo IVGTT.