Table 4. Presence of mutations in the gyrA and parC genes in 76 ciprofloxacin-resistant Escherichia coli isolated from 20 healthy chicken farms in the region of Dakar, Senegal.
Amino acid changes in gyrA | Amino acid changes in parC | No. of isolates carrying mutation(s) (% and 95%CI) | No. of farms of origin (% and 95%CI) | ||
---|---|---|---|---|---|
Ser83 | Asp87 | Ser80 | Glu84 | ||
Leu | Asn | Ile | - | 62 (82.2; 76.5–87.9) | 19 (95.0; 75.1–99.9) |
Leu | Asn | - | Lys | 1 (1.7; 0.0–5.3) | 1 (5.0; 0.1–24.8) |
Leu | Asn | Ile | Gly | 2 (2.3; 0.0–5.6) | 2 (10.0; 1.2–31.7) |
Leu | Asn | Arg | - | 1 (1.9; 0.0–5.2) | 0 (0.0; 0.0–16.8) a |
Leu | Asn | - | - | 2 (2.3; 0.0–5.7) | 2 (10.0; 1.2–31.7) |
Tyr | Asn | - | - | 1 (0.8; 0.0–2.2) | 1 (5.0; 0.1–24.8) |
Leu | - | Ile | - | 3 (4.7; 0.0–9.5) | 2 (10.0; 1.2–31.7) |
- | - | Ile | - | 2 (1.9; 0.0–5.9) | 2 (10.0; 0.0–23.2) |
- | - | - | - | 2 (1.7; 0.0–4.5) | 2 (10.0; 1.2–31.7) |
aPrevalence at farm level was computed using feaces and drinking water sample and the isolate carrying these mutations was from rinsing water; Ser, serine; Leu, leucine; Tyr, tyrosine; Asp, aspartic acid; Asn, asparagine; Ile, isoleucine; Arg, arginine; Glu, glutamic acid; Lys, lysine.