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. 2019 Mar 26;14(3):e0214304. doi: 10.1371/journal.pone.0214304

Table 4. Presence of mutations in the gyrA and parC genes in 76 ciprofloxacin-resistant Escherichia coli isolated from 20 healthy chicken farms in the region of Dakar, Senegal.

Amino acid changes in gyrA Amino acid changes in parC No. of isolates carrying mutation(s) (% and 95%CI) No. of farms of origin (% and 95%CI)
Ser83 Asp87 Ser80 Glu84
Leu Asn Ile - 62 (82.2; 76.5–87.9) 19 (95.0; 75.1–99.9)
Leu Asn - Lys 1 (1.7; 0.0–5.3) 1 (5.0; 0.1–24.8)
Leu Asn Ile Gly 2 (2.3; 0.0–5.6) 2 (10.0; 1.2–31.7)
Leu Asn Arg - 1 (1.9; 0.0–5.2) 0 (0.0; 0.0–16.8) a
Leu Asn - - 2 (2.3; 0.0–5.7) 2 (10.0; 1.2–31.7)
Tyr Asn - - 1 (0.8; 0.0–2.2) 1 (5.0; 0.1–24.8)
Leu - Ile - 3 (4.7; 0.0–9.5) 2 (10.0; 1.2–31.7)
- - Ile - 2 (1.9; 0.0–5.9) 2 (10.0; 0.0–23.2)
- - - - 2 (1.7; 0.0–4.5) 2 (10.0; 1.2–31.7)

aPrevalence at farm level was computed using feaces and drinking water sample and the isolate carrying these mutations was from rinsing water; Ser, serine; Leu, leucine; Tyr, tyrosine; Asp, aspartic acid; Asn, asparagine; Ile, isoleucine; Arg, arginine; Glu, glutamic acid; Lys, lysine.