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. Author manuscript; available in PMC: 2020 Feb 21.
Published in final edited form as: Cell. 2019 Jan 24;176(5):1128–1142.e18. doi: 10.1016/j.cell.2018.12.023

Figure 2. Collateral arteries are formed by arterial endothelial cells. See also Figure S3.

Figure 2.

(A) Experimental design where non-labeled arteries are black and lineage-labeled capillaries or arteries are magenta or red, respectively. Boxes localize collateral arteries in B and C. (B and C) CX40+ collateral arteries (dotted lines) showed minimal ApjCreER lineage labeling from capillaries (B), but heavy lineage-labeling Cx40CreER+ arteries (C). (D) Quantification of B and C (n=7 arteries each). Lig LCA, ligated left coronary artery; MI, myocardial infarction; RCA, right coronary artery; Tam, Tamoxifen; P, postnatal; EC, endothelial cells; brch, branch. Scale bars: 100μm. Error bars are st dev: ****, p≤0.0001.