FIG. 3.

Topological filtering of GDD values using OMST. (A) Dissimilarity matrix of subject-specific FCGs (N = 132) based on the GDD metric. (B) MDS was applied to the dissimilarity matrix of GDD values, which were rescaled and projected in a common three-dimensional space. Stress indicates the % loss of information due to the dimensionality reduction process via the MDS algorithm. GDD, graph diffusion distance; HA, healthy adults; HC, typically developing (healthy) children; MDS, multidimensional scaling; mTBI, mild traumatic brain injury patients; R1, R2, and R3 indicate the three predetermined dimensions used to plot participant cases through MDS; RD, reading-disabled children. Color images available online at www.liebertpub.com/brain