FIG. 5.

(A) Unsupervised clustering of subjects based on the correlation between predefined DMN seed and the nine ROIs that survived between-group second-level DMN analysis. First two principal components applied for visualization purpose; each subject is identified by numbers; each cluster is represented by a different color. (B) Minimum spanning tree (MST) of individual subjects from the nine ROIs that survived between-group analysis at the second level. Shades of blue: positively correlated nodes with the DMN; shades of yellow: negatively correlated nodes with the DMN. Red frame: atypical topology; green frame: typical topology (defined as cohesive cluster of positively correlated nodes).