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. 2017 Aug 20;27(6):345–362. doi: 10.1089/ars.2016.6758

FIG. 5.

FIG. 5.

Blockade of CXCR4 signaling preserves podocyte integrity after oxidative stress. (A) Representative images show immunofluorescence staining of nephrin, WT1, and podocalyxin (Podx) and PAS staining. Scale bar, 20 μm. (B–D) Western blotting analyses (B) and quantitative graphs of nephrin (C) and podocalyxin (Podx) (D) in different groups. Numbers (1 and 2) represent different animals in a given group. *p < 0.05 versus ADR group; †p < 0.05 versus ADR or ADR plus AOPPs vehicle controls (n = 5–6). (E) Quantitative analysis shows glomerular sclerosis score in different groups as indicated. (F) Urinary albumin levels in different groups of mice. Urinary albumin is expressed as mg/mg of creatinine. *p < 0.05 versus ADR group; †p < 0.05 versus ADR or ADR plus AOPPs vehicle controls (n = 5–6). All full unedited gels for Figure 5 are presented in Supplementary Figure S9.