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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Ophthalmology. 2018 Oct 31;126(4):591–600. doi: 10.1016/j.ophtha.2018.10.037

Table 4.

Mean RIT (minutes) as a function of total number of risk alleles for CFH and ARMS2 stratified by normal and AMD eyes

Normal macular health AMD
Number
of alleles		 N Mean
(standard
deviation)		 p-value Adjusted
p-value2 		N Mean
(standard
deviation)		 p-value Adjusted p-
value2
0 84 9.9
(2.8)		 0.0048 0.0002 32 12.8
(8.9)		 0.0038 <0.0001
1 175 10.7
(4.7)		 49 13.2
(9.3)
2 118 12.5
(7.7)		 43 19.5
(12.8)
3 31 12.1
(5.8)		 11 22.2
(13.2)
41 0 1
1

There were no normal eyes having 4 risk alleles. There was one eye in the AMD group with 4 risk alleles. The RIT for this person was 18.6 minutes. The 4-allele category was not included in the comparison among groups for the AMD eyes.

2

Adjusted for age and smoking