Figure 5.
Prior appetitive conditioning history with nicotine as a CS selectively reduced methamphetamine intake in females. A) Mean(±SEM) methamphetamine infusion taken during self-administration in the male nicotineCS and pseudoCS groups. B) Mean(±SEM) methamphetamine infusion taken during self-administration in the female nicotineCS and pseudoCS groups. NicotineCS trained females self-administered less methamphetamine than the pseudoCS females. ^ - indicates significant main effect of Conditioning History, p = 0.001.