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. 2018 Jan 10;38(1):BSR20171109. doi: 10.1042/BSR20171109

Figure 5. miR-27b and siRNA-Pparγ inhibit the production of lipid droplets in hypertrophy-enhancing medium.

Figure 5

(A) Hypertrophic chondrocytes were treated with siRNA-Pparγ, miR-27b mimicNC-mimic, and transfection control, respectively. Seven days after induction of hypertrophy in differentiation medium, chondrocytes became adipocytes. Lipid droplets (red) in chondrocytes are revealed by Oil Red O staining. Bar: 50 µm. (B) The integrated optical density (IOD) of lipid droplets decreased significantly in miR-27b mimic-transfected cells and siRNA-Pparγ-transfected cells compared with the NC and transfection control group of cells (n=5, *P<0.05, **P<0.01).