Table 2. Univariate analysis to identify variables associated with anti-HBs seroconversion rate on the two vaccination schedules.
| Variable | Accelerated schedule | Standard schedule | χ2 | P | |
|---|---|---|---|---|---|
| Seroconversion % (n/N) | Seroconversion % (n/N) | ||||
| Age, year | 15–29 | 93.3 (56/60) | 94.2 (49/52) | 1.000† | |
| 30–49 | 85.4 (76/89) | 90.7 (97/107) | 1.737 | 0.187 | |
| 50–59 | 73.1 (38/52) | 85.1 (40/47) | 2.617 | 0.106 | |
| χ2 | 8.620 | 3.747 | |||
| P | 0.003* | 0.053* | |||
| Sex | Male | 79.5 (58/73) | 90.0 (72/80) | 4.520 | 0.034 |
| Female | 87.5 (112/128) | 90.5 (114/126) | 0.384 | 0.759 | |
| χ2 | 2.308 | 0.002 | |||
| P | 0.129 | 0.960 | |||
| BMI | <18.5 | 100 (20/20) | 95.0 (19/20) | 1.000† | |
| 18.5–23.9 | 89.2 (91/102) | 92.8 (103/111) | 1.203 | 0.273 | |
| 24–27.9 | 75.0 (45/60) | 89.8 (53/59) | 5.289 | 0.021 | |
| ≥28 | 73.7 (14/19) | 68.8 (11/16) | 0.043 | 0.836 | |
| χ2 | 10.206 | 9.866 | |||
| P | 0.001* | 0.002* | |||
| Smoking | Yes | 78.8 (26/33) | 86.4 (38/44) | 3.833 | 0.052 |
| No | 85.7 (144/168) | 92.1 (116/126) | 0.748 | 0.387 | |
| χ2 | 1.014 | 2.177 | |||
| P | 0.314 | 0.140 | |||
| Drinking | |||||
| (g/day) | No | 86.6 (129/149) | 91.3 (136/149) | 2.354 | 0.125 |
| <20 | 80.0 (20/25) | 87.9 (29/33) | 0.494† | ||
| ≥20 | 77.8 (21/27) | 87.5 (21/24) | 0.315† | ||
| P | 0.335† | 0.551† | |||
| Anti-HBc | Negative | 90.0 (99/110) | 93.8 (105/112) | 1.312 | 0.252 |
| Positive | 78.0 (71/91) | 86.2 (81/94) | 2.904 | 0.088 | |
| χ2 | 5.478 | 4.349 | |||
| P | 0.019 | 0.037 | |||
| Family history of hepatitis B | Yes | 100 (3/3) | 100 (2/2) | ||
| No | 84.3 (167/198) | 90.2 (184/204) | 4.069 | 0.044 | |
| P | 1.000† | 1.000 | |||
*
Cochran–Armitage trend test.
†
Fisher’s exact test.