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. 2019 Mar 20;7:56. doi: 10.3389/fpubh.2019.00056

Table 2.

Size and cost estimates for vaccine manufacturing site scenarios.

Components of a vaccine manufacturing site First scenario Second scenario Third scenario
Cost per sq. foot (USD) Area size (sq. feet) Cost (USD) Million Area size (sq. feet) Cost (USD) Million Area size (sq. feet) Cost (USD) Million
Master cell bank 1,000 1,000 1.00 250 0.25 250 0.25
Bulk production 1,250 80,000 100.00 20,000 25.00 20,000 25.00
Formulation 1,500 17,000 25.50 4,250 6.38 17,000 25.50
Filling 2,000 40,000 80.00 10,000 20.00 20,000 40.00
Packaging 1,000 40,000 40.00 10,000 10.00 20,000 20.00
QC&QA 500 30,000 15.00 7,500 3.75 30,000 15.00
Animal house 500 3,000 1.50 750 0.38 3,000 1.50
Warehouse 300 30,000 9.00 7,500 2.25 30,000 9.00
Administration 400 7,500 3.00 1,875 0.75 1,875 0.75
Guard house 300 500 0.15 125 0.04 125 0.04
Central Utilities 500 6,000 3.00 1,500 0.75 1,500 0.75
Canteen 400 3,000 1.20 750 0.30 750 0.30
Subtotal 279.35
Estimate for 25% over capacity 804 64,500 52.00
Estimate for preparation of 50% future extension 100 129,000 13.00
Total 344.12 69.84 138.09