Table 2.
Components of a vaccine manufacturing site | First scenario | Second scenario | Third scenario | ||||
---|---|---|---|---|---|---|---|
Cost per sq. foot (USD) | Area size (sq. feet) | Cost (USD) Million | Area size (sq. feet) | Cost (USD) Million | Area size (sq. feet) | Cost (USD) Million | |
Master cell bank | 1,000 | 1,000 | 1.00 | 250 | 0.25 | 250 | 0.25 |
Bulk production | 1,250 | 80,000 | 100.00 | 20,000 | 25.00 | 20,000 | 25.00 |
Formulation | 1,500 | 17,000 | 25.50 | 4,250 | 6.38 | 17,000 | 25.50 |
Filling | 2,000 | 40,000 | 80.00 | 10,000 | 20.00 | 20,000 | 40.00 |
Packaging | 1,000 | 40,000 | 40.00 | 10,000 | 10.00 | 20,000 | 20.00 |
QC&QA | 500 | 30,000 | 15.00 | 7,500 | 3.75 | 30,000 | 15.00 |
Animal house | 500 | 3,000 | 1.50 | 750 | 0.38 | 3,000 | 1.50 |
Warehouse | 300 | 30,000 | 9.00 | 7,500 | 2.25 | 30,000 | 9.00 |
Administration | 400 | 7,500 | 3.00 | 1,875 | 0.75 | 1,875 | 0.75 |
Guard house | 300 | 500 | 0.15 | 125 | 0.04 | 125 | 0.04 |
Central Utilities | 500 | 6,000 | 3.00 | 1,500 | 0.75 | 1,500 | 0.75 |
Canteen | 400 | 3,000 | 1.20 | 750 | 0.30 | 750 | 0.30 |
Subtotal | 279.35 | ||||||
Estimate for 25% over capacity | 804 | 64,500 | 52.00 | ||||
Estimate for preparation of 50% future extension | 100 | 129,000 | 13.00 | ||||
Total | 344.12 | 69.84 | 138.09 |