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. 2018 Dec 7;38(6):BSR20180767. doi: 10.1042/BSR20180767

Figure 6. ChREBP mediated inflammatory reactions in mesangial cells induced by glucose administration.

Figure 6

SV40 MES 13 cells were transfected with control siRNA or siRNA against ChREBP for 48 h, the mRNA (A) and protein (B) levels of ChREBP were determined by real-time PCR and Western blot assay, respectively. SV40 MES 13 cells were transfected with control siRNA or siRNA against ChREBP for 24 h and treated with 5, 15, and 50 mM glucose for additional 48 h, the levels of inflammatory cytokines including TNF-α (C), IL-1β (D), and IL-6 (E) were determined by ELISA; **P<0.01, ***P<0.001.