Table 2. Allele and genotype frequencies of the selected SNPs with respective P-values, OR, and confidence interval.
| SNP | Gene | MAF (%) | Genotype frequency (%) | P-value | OR (CI) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Obese | Non obese | Obese | Non obese | ||||||||
| Homozygous common | Heterozygous | Homozygous minor | Homozygous common | Heterozygous | Homozygous minor | ||||||
| G2548A | LEP | 42.8 | 30.1 | 34.8 | 44.7 | 20.5 | 51.1 | 37.5 | 11.3 | 0.028 | 1.63 (1.07–2.48) |
| Gln223Arg | LEPR | 32 | 18.6 | 55.2 | 26 | 18.8 | 71.6 | 19.1 | 9.3 | 5.4 × 10−6 | 1.11 (0.98–2.21) |
| Ala54Thr | FABP2 | 42.4 | 33.1 | 35.7 | 43.4 | 20.9 | 50.2 | 37.6 | 12.2 | 0.002 | 1.56 (0.102–0.364) |
| rs9939609 | FTO | 35.1 | 27.5 | 52.9 | 35.7 | 11.5 | 57.9 | 37.1 | 5.0 | 0.017 | 2.36 (1.14–4.86) |
| rs3923113 | GRB14 | 24.5 | 21.9 | 58.7 | 33.5 | 7.8 | 59.9 | 36.5 | 3.7 | 0.20 | 0.88 (0.63–1.25) |
| rs16861329 | ST6GAL1 | 23.2 | 17.8 | 58.6 | 36.5 | 5.0 | 67.8 | 28.9 | 3.3 | 0.13 | 0.76 (0.53–1.08) |
| rs1802295 | VPS26A | 29.4 | 23 | 52.5 | 36.2 | 11.3 | 58.1 | 37.7 | 4.2 | 0.02 | 1.42 (1.03–1.95) |
| rs7178572 | HMG20A | 52.9 | 52.1 | 19.6 | 53.4 | 26.9 | 28.6 | 38.6 | 32.9 | 0.007 | 1.06 (0.82–1.37) |
| rs2028299 | AP3S2 | 33.2 | 26.9 | 47.1 | 39.5 | 13.5 | 52.4 | 41.4 | 6.2 | 0.04 | 1.33 (0.98–1.81) |
| rs4812829 | HNF4A | 31 | 24.8 | 50.5 | 37.2 | 12.4 | 55.2 | 40.0 | 4.8 | 0.02 | 1.34 (0.98–1.84) |