Table 3.
Frequency of impairment of different cognitive domains in CIS (BRB-N).
| References | N CIS | IPS | Memory | EF | WM |
|---|---|---|---|---|---|
| Reuter et al. (20) | 97 | SDMT 20% | SRT LTS 15% SRT DR 28% SPART 20% SPART DR 17% | WLG (P) 28% WLG (S) 20% | PASAT 3 22% |
| Vitterbo et al. (22) | 100 | SDMT 7% | SRT LTS 7% SRT DR 9% SPART 7% SPART DR 2% | WLG 22% | PASAT 3 7% |
| Ruano et al. (10) | 167 | IPS* (SDMT/PASAT) 41% | Verbal learning* (SRT) 27% Visuo-spatial* (SPART) 14.5% | EF* (WLG, Stroop) 42% |
CIS, clinically isolated syndromes; IPS, information processing speed; EF, executive functions; WM, working memory. SDMT, Symbol-Digit modalities test; SRT, Selective Reminding test; LTS, Long-term storage; DR, delayed recall; SPART, Spatial Recall test; PASAT, Paced-Auditory Serial Addition test; WLG, Word List Generation test (P, phonemic; S, semantic).
*
At least one test score impaired.