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. 2019 Mar 20;9:173. doi: 10.3389/fonc.2019.00173

Figure 2.

Figure 2

There were three arms in the animal study: AHCC supplementation arm (N = 10), no supplementation control arm (N = 10) and a vehicle (autoclaved water) control arm (N = 10). The AHCC supplementation arm received an oral dose (50 mg/kg, in 0.25 mL, gastric gavage); the no supplementation control had no study intervention, and the vehicle control arm received an oral dose of autoclaved water (0.25 mL, gastric gavage) per day starting on day zero and continued until completion of the study (day 90). TX1 represents at end of treatment and TX2 represents study day 90 which was 30 days after stopping AHCC supplementation. The absence of HR-HPV in the SiHa cell lines at TX1 and TX2 confirmed clearance of HR-HPV. NT, non-treatment control; VC, vehicle/placebo control.