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. 2018 May 28;38(3):BSR20180503. doi: 10.1042/BSR20180503

Figure 1. Effect of Piperine on cell viability of human ovarian cancer A2780 cells and human ovarian epithelial OSE cells.

Figure 1

(A) The chemical structure of Piperine. (B) Effect of Piperine (0, 4, 8, 16, or 20 μM) on cell viability of ovarian cancer cell line A2780 at 48 h. (C) Effect of Piperine (20 μM) on cell viability of ovarian cancer cell line A2780 at 12, 24, 48, and 72 h. (D) Effect of Piperine (0, 4, 8, 16, or 20 μM) on cell viability of normal ovarian cell line OSE at 48 h. (E) Effect of Piperine (20 μM) on cell viability of normal ovarian cell line OSE at 12, 24, 48, and 72 h. (F) Effect of Piperine (8, 16, or 20 μM) treatment for 48 h on the morphological changes of ovarian cancer cell line A2780 and the representative images were photographed with inverted contrast microscopy at 200× magnification. Data shown are mean ± SD of three similar experiments. *P<0.05 and **P<0.01 as compared with the control group.