(A) The morphology of the cell nucleus in ovarian cancer cell line A2780 treated with Piperine (0, 8, 16, or 20 μM) was observed after DAPI staining by fluorescence microscopy at 100× magnification. Nuclear condensation and apoptotic bodies were indicated by the arrows. (B) Effect of Piperine (0, 8, 16, or 20 μM) on the percentages of apoptotic cells of ovarian cancer cell line A2780 (including early stage and late stage) by quantification of FACS analysis. Data shown are mean ± SD of three similar experiments. *P<0.05 and **P<0.01 as compared with the control group.