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. 2018 May 28;38(3):BSR20180503. doi: 10.1042/BSR20180503

Figure 4. Piperine induces apoptotic cell death via modulation of JNK and p38 MAPK signaling pathways in human ovarian cancer A2780 cells.

Figure 4

(A) Effect of Piperine (0, 8, 16, or 20 μM) on phosphorylation of JNK of ovarian cancer cell line A2780. (B) Effect of Piperine (0, 8, 16, or 20 μM) on p38 MAPK of ovarian cancer cell line A2780. (C) Effect of JNK-inhibitor or p38 MAPK inhibitor on apoptosis of ovarian cancer cell line A2780 induced by Piperine (20 μM). Data shown are mean ± SD of three similar experiments. *P<0.05, **P<0.01 and ***P<0.01 as compared to the control group.