Table 2.
Degree centrality differences between patients with early BD and HCs during the resting state.
| Comparison | MNI Coordinates | T | Voxels | ROI | ||
|---|---|---|---|---|---|---|
| Brain region | X | Y | Z | |||
| BD<HC | ||||||
| Posterior Lobe of the Cerebellum* | −6 | −57 | −54 | 4.663 | 66 | 1 |
| Right Superior Temporal Gyrus* | 60 | −12 | 0 | 4.205 | 18 | 2 |
| Bilateral Superior Frontal Gyrus, Medial Frontal Gyrus, and Supplementary Motor Area* | −3 | −12 | 75 | 5.445 | 76 | 3 |
| BD>HC | ||||||
| Right Inferior Temporal Gyrus* | 51 | −39 | −24 | −4.426 | 20 | 4 |
| Right Inferior Temporal Gyrus* | 57 | −45 | −15 | −3.782 | 12 | 4a |
| Right Orbital Part of the Middle Frontal Gyrus* | 33 | 39 | −12 | −4.415 | 19 | 5 |
| Right Precentral Gyrus and Postcentral Gyrus* | 33 | −30 | 42 | −4.923 | 60 | 6 |
BD, bipolar disorder; HC, healthy control; MNI, Montreal Neurological Institute space; ROI, region of interest for correlation analyses; FWHM, full-width at half-maximum.
*
Regions showing significant differences after AlphaSim correction (cluster connection radius = 4 mm, 5,000 simulations, FWHM = 6 mm, voxel P = 0.001, and cluster size ≥12 voxels).