Table 5. Variations of indices in ALT <40 and ALT >40 group after Lira treatment for 12 weeks.
Term | ALT <40 (n=29) | ALT >40 (n=23) | t | P |
---|---|---|---|---|
Age (year) | 57.3 ± 5.8 | 60.1 ± 4.9 | −1.85 | 0.07 |
Gender ratio (male/female) | 16/14 | 15/8 | - | 0.533 |
Weight (kg) | 75.33 ± 5.66 | 78.92 ± 4.56 | −1.78 | 0.08 |
BMI (kg/m2) | 24.93 ± 1.02 | 27.05 ± 0.862 | −7.97 | 0.000 |
WHR | 0.93 ± 0.04 | 0.98 ± 0.071 | −2.19 | 0.033 |
TC (mmol/l) | 4.72 ± 0.63 | 5.08 ± 0.461 | −2.30 | 0.026 |
TG (mmol/l) | 1.78 ± 0.21 | 1.93 ± 0.37 | −1.84 | 0.071 |
LDL (mmol/l) | 2.39 ± 0.29 | 2.55 ± 0.271 | −2.04 | 0.047 |
HDL (mmol/l) | 1.02 ± 0.24 | 1.09 ± 0.21 | −1.10 | 0.275 |
FPG (mmol/l) | 6.75 ± 0.33 | 7.56 ± 0.342 | −8.67 | 0.000 |
2hPG (mmol/l) | 9.75 ± 1.79 | 11.03 ± 2.521 | −2.41 | 0.037 |
HbA1C (%) | 7.14 ± 0.45 | 7.35 ± 0.57 | −1.49 | 0.144 |
HOMA-IR | 2.29 ± 0.35 | 2.69 ± 0.382 | −3.94 | 0.000 |
APN (mg/l) | 9.48 ± 2.15 | 10.87 ± 2.041 | −2.37 | 0.021 |
CRP (mg/l) | 2.07 ± 0.19 | 2.32 ± 0.222 | −4.39 | 0.000 |
Compared with the ALT <40 group.
1P<0.05 .
2P<0.01 (unpaired t test).
3Chi-square test.