Table 5. Assessment of potential sources of heterogeneity amongst studies by meta-regression.
Covariates | Outcomes | P-value | Regression coefficient (95% CI) |
---|---|---|---|
Tumor type (UTUC compared with BC) | |||
OS | 0.82 | 0.92 (0.36–2.37) | |
CSS | 0.15 | 0.52 (0.20–1.35) | |
RFS | 0.02 | 0.27 (0.18–0.79) | |
30dC | 0.03 | 0.48 (0.25–0.92) | |
90dM | 0.02 | 0.36 (0.18–0.74) | |
Ethnicity (Asian compared with non-Asian) | |||
OS | 0.10 | 1.68 (0.90–3.14) | |
CSS | 0.81 | 1.11 (0.39–3.16) | |
RFS | 0.43 | 1.58 (0.37–6.80) | |
Analysis type (univariate compared with multivariate) | |||
OS | 0.74 | 0.88 (0.36–2.10) | |
CSS | 0.54 | 0.77 (0.29–2.04) | |
RFS | 0.05 | 0.39 (0.19–1.02) | |
30dC | 0.16 | 0.62 (0.30–1.30) | |
90dM | 0.66 | 0.66 (0.06–7.13) | |
Cut-off value (3.5 g/dl compared with others) | |||
OS | 0.08 | 2.50 (0.89–7.01) | |
CSS | 0.72 | 0.86 (0.32–2.30) | |
RFS | 0.78 | 1.18 (0.27–5.22) | |
30dC | 0.32 | 0.64 (0.21–1.92) | |
90dM | 0.42 | 0.52 (0.07–4.04) | |
Sample size (>600 compared with ≤600) | |||
OS | 0.46 | 1.38 (0.54–3.49) | |
RFS | 0.40 | 1.63 (0.38–6.97) | |
30dC | 0.35 | 1.64 (0.47–5.72) | |
90dM | 0.82 | 1.20 (0.16–9.20) |