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. 2018 Dec 21;38(6):BSR20180741. doi: 10.1042/BSR20180741

Figure 5. Down-regulation of HIF-1α inhibited PI3K/AKT pathway and VEGF.

Figure 5

This figure shows the effects of HIF-1α siRNA silencing on expression of VEGF (A) and phosphorylation and expression of AKT (B). In (A,B) the upper part is Western blot results and the lower part is the normalized expression. HIF-1α siRNA silencing inhibited VEGF expression and AKT phosphorylation. *, P<0.05.