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. 2018 Dec 21;38(6):BSR20180978. doi: 10.1042/BSR20180978

Figure 2. Effects of miR-141 on CRC cells migration and invasion.

Figure 2

For the wound-healing and invasion assay, CRC cells were seeded and transfected with miR-141 mimics, miR-141 inhibitor and the NC for 24 h. (A) Wounds healing from a representative experiment of the HCT-116 cell. (B) The wound-healing rate in CRC cells transfected with miR-141 mimics was significantly decreased, while accelerated in CRC cells transfected with miR-141 inhibitor compared with the NC. (C and D) Representative images of the transwell invasion assay. The normal ratio of invasive cells is shown. Up-regulation of miR-141 in CRC cells reduced cell invasion, while inhibition of miR-141 expression increased cell invasion; n=3, *P<0.05, **P<0.01.