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. 2018 Dec 21;38(6):BSR20180978. doi: 10.1042/BSR20180978

Figure 4. 5-FU treatment suppressed CRC cells movement via regulating miR-141-mediated MAP4K4 axis.

Figure 4

(A and B) representative results of colony formation of 5-FU, miR-141 mimics, combination of the two and NC. (C and D) Wound-healing assay was conducted and phase-contrast images were obtained immediately after wounding and at 48 h. (E and F) Invasion assay was performed. Representative images were recorded. (G and H) Expression level of MAP4K4 mRNA and proteins were assessed in CRC cells treated by 5-FU, miR-141 mimics, combination of the two and NC; n=3, *P<0.05, **P<0.01.