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. 2018 Dec 21;38(6):BSR20180978. doi: 10.1042/BSR20180978

Figure 6. miR-141 and 5-FU could reverse the colon cancer tumorigenesis.

Figure 6

Each representative images treatment group are presented the effect of 5-FU, miR-141, and combined the two on colon tumors in the nude mice. (A) Phase-contrast and flurescence images of HCT-116 transfected with lenti-miR-141. (B) RT-qPCR analysis of miR-141 in HCT-116 transfected with Lenti-miR-141 or Lenti-NC. (C, D, and E) Tumor weight and volume of lenti-NC+5-FU, lenti-NC, lenti-miR-141 + 5FU, and lenti-miR-141 cells were recorded. (F) The expression levels of MAP4K4, Ki-67, and MMP9 in the tumors tissues of mice in different groups were determined by immunohistochemistry (×200); n=3, **P<0.01.