Table 1. CSNA baroreceptor sensitivity and X-intercept in response to vehicle control and incremental doses of 6, 24, and 48 ng/kg/min Ang II each infused for 30 min. Values shown as mean ± S.E.M.
Baseline | Low dose 6 ng/kg/min Ang II | Medium dose 24 ng/kg/min Ang II | High dose 48 ng/kg/min Ang II | ||
---|---|---|---|---|---|
CSNA baroreceptor sensitivity (burst/100 beats/mmHg) | Control | 5.79 ± 0.59 | 5.87 ± 1.20 | 5.74 ± 0.79 | 5.57 ± 2.58 |
Ang II | 6.99 ± 1.02 | 6.34 ± 1.03 | 5.65 ± 0.44 | 5.61 ± 0.68 | |
X-intercept | Control | 101.7 ± 4.81 | 102.7 ± 4.22 | 103.9 ± 3.76 | 106.0 ± 4.22 |
Ang II | 109.6 ± 3.58 | 108.6 ± 3.58 | 113.1 ± 3.23 | 113.3 ± 2.28 | |
HR baroreceptor sensitivity (ms/mmHg) | Control | 16.4 ± 0.95 | 17.1 ± 0.85 | 17.5 ± 1.45 | 16.5 ± 1.34 |
Ang II | 18.1 ± 1.59 | 18.0 ± 1.54 | 19.0 ± 1.02 | 17.8 ± 1.43 |