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. 2018 Dec 18;38(6):BSR20181803. doi: 10.1042/BSR20181803

Figure 5. PKC-α mediated cisplatin-induced Gal-3 expression.

Figure 5

(A) HEK293 cells were pre-incubated with 2 μM PDB (Sigma–Aldrich, St. Louis, MO, U.S.A.) and 10 μM chelerythrine (che) for 30 min then treated with or without 2 μM cisplatin (CP) treatment. (B) The representative levels of PKC-α and Gal-3 in the HEK 293 cells. *P<0.05 vs Ctrl in Mock, #P<0.05. (C) HEK293 cells were transfected with 2 μg/well of pcDNA3-PKC-α or vector alone. Gal-3 and PKC-α levels were examined by Western blot. (D) Quantification of Gal-3 and PKC-α levels based on Western blot; *P<0.05.