Table 4. Correlations of CACNA 1A, CACNA 1C, and CACNA 1H genotypes with BMI, 2 h PG, HbA1c, and TG in the DPN group.
Genotype | BMI (kg/m2) | 2 h PG (mmol/l) | HbA1c (%) | TG (mmol/l) |
---|---|---|---|---|
CACNA 1A | ||||
rs2248069 | ||||
AA | 25.59 ± 3.24 | 14.96 ± 4.29 | 10.71 ± 3.26 | 4.69 ± 1.53 |
GA + GG | 25.35 ± 3.33 | 14.49 ± 4.51 | 7.83 ± 2.49 | 2.99 ± 1.31 |
P | 0.960 | 0.603 | <0.001 | <0.001 |
rsl6030 | ||||
CC | 25.57 ± 3.08 | 14.56 ± 3.93 | 8.93 ± 3.31 | 4.01 ± 1.49 |
CT + TT | 25.09 ± 3.55 | 14.64 ± 5.19 | 7.92 ± 2.54 | 2.56 ± 1.24 |
P | 0.390 | 0.913 | 0.037 | <0.001 |
CACNA 1C | ||||
rs216008 | ||||
CC | 25.53 ± 3.31 | 14.96 ± 4.10 | 9.14 ± 3.23 | 4.01 ± 1.55 |
CT + TT | 25.26 ± 3.30 | 14.34 ± 4.61 | 7.89 ± 2.49 | 2.99 ± 1.41 |
P | 0.633 | 0.459 | 0.004 | <0.001 |
rs2239050 | ||||
GG | 25.47 ± 3.32 | 14.62 ± 4.04 | 9.15 ± 3.29 | 4.02 ± 1.47 |
GC + CC | 25.27 ± 3.42 | 14.47 ± 5.0. | 7.92 ± 2.46 | 2.81 ± 1.39 |
P | 0.715 | 0.945 | 0.010 | <0.001 |
CACNA 1H | ||||
rs3794619 | ||||
TT | 25.33 ± 3.12 | 14.65 ± 4.04 | 9.15 ± 3.29 | 4.04 ± 1.48 |
TC + CC | 25.39 ± 3.43 | 14.54 ± 4.96 | 7.92 ± 2.46 | 2.83 ± 1.37 |
P | 0.923 | 0.885 | 0.012 | <0.001 |
rs7191246 | ||||
GG | 25.48 ± 3.15 | 14.63 ± 3.89 | 8.93 ± 3.10 | 3.98 ± 1.48 |
GC + CC | 25.20 ± 3.52 | 14.54 ± 5.40 | 7.85 ± 2.56 | 2.53 ± 1.24 |
P | 0.615 | 0.908 | 0.029 | <0.001 |