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. 2018 May 28;38(3):BSR20171670. doi: 10.1042/BSR20171670

Table 4. Correlations of CACNA 1A, CACNA 1C, and CACNA 1H genotypes with BMI, 2 h PG, HbA1c, and TG in the DPN group.

Genotype BMI (kg/m2) 2 h PG (mmol/l) HbA1c (%) TG (mmol/l)
CACNA 1A
rs2248069
AA 25.59 ± 3.24 14.96 ± 4.29 10.71 ± 3.26 4.69 ± 1.53
GA + GG 25.35 ± 3.33 14.49 ± 4.51 7.83 ± 2.49 2.99 ± 1.31
P 0.960 0.603 <0.001 <0.001
rsl6030
CC 25.57 ± 3.08 14.56 ± 3.93 8.93 ± 3.31 4.01 ± 1.49
CT + TT 25.09 ± 3.55 14.64 ± 5.19 7.92 ± 2.54 2.56 ± 1.24
P 0.390 0.913 0.037 <0.001
CACNA 1C
rs216008
CC 25.53 ± 3.31 14.96 ± 4.10 9.14 ± 3.23 4.01 ± 1.55
CT + TT 25.26 ± 3.30 14.34 ± 4.61 7.89 ± 2.49 2.99 ± 1.41
P 0.633 0.459 0.004 <0.001
rs2239050
GG 25.47 ± 3.32 14.62 ± 4.04 9.15 ± 3.29 4.02 ± 1.47
GC + CC 25.27 ± 3.42 14.47 ± 5.0. 7.92 ± 2.46 2.81 ± 1.39
P 0.715 0.945 0.010 <0.001
CACNA 1H
rs3794619
TT 25.33 ± 3.12 14.65 ± 4.04 9.15 ± 3.29 4.04 ± 1.48
TC + CC 25.39 ± 3.43 14.54 ± 4.96 7.92 ± 2.46 2.83 ± 1.37
P 0.923 0.885 0.012 <0.001
rs7191246
GG 25.48 ± 3.15 14.63 ± 3.89 8.93 ± 3.10 3.98 ± 1.48
GC + CC 25.20 ± 3.52 14.54 ± 5.40 7.85 ± 2.56 2.53 ± 1.24
P 0.615 0.908 0.029 <0.001