Table 5. Correlations of CACNA 1A, CACNA 1C, and CACNA 1H genotype and allele frequencies with BMI, 2 h PG, HbA1c, and TG in the non-DPN group.
Genotype | BMI (kg/m2) | 2 h PG (mmol/l) | HbA1c (%) | TG (mmol/l) |
---|---|---|---|---|
CACNA 1A | ||||
rs2248069 | ||||
AA | 25.89 ± 3.16 | 14.68 ± 4.66 | 11.55 ± 2.85 | 4.02 ± 1.09 |
GA + GG | 25.01 ± 3.78 | 14.99 ± 4.30 | 9.17 ± 2.69 | 3.62 ± 1.43 |
P | 0.192 | 0.967 | <0.001 | 0.046 |
rsl6030 | ||||
CC | 25.60 ± 3.43 | 14.63 ± 4.63 | 10.33 ± 3.12 | 4.20 ± 1.04 |
CT + TT | 24.95 ± 3.61 | 14.61 ± 3.90 | 9.08 ± 2.47 | 2.90 ± 1.46 |
P | 0.338 | 0.929 | 0.030 | <0.001 |
CACNA 1C | ||||
rs216008 | ||||
CC | 25.38 ± 3.35 | 14.50 ± 4.62 | 10.70 ± 3.10 | 4.27 ± 1.04 |
CT + TT | 25.34 ± 3.70 | 14.87 ± 4.15 | 9.00 ± 2.55 | 3.18 ± 1.41 |
P | 0.997 | 0.684 | 0.001 | <0.001 |
rs2239050 | ||||
GG | 25.16 ± 3.41 | 14.69 ± 4.54 | 10.45 ± 3.10 | 4.24 ± 1.04 |
GC + CC | 25.69 ± 3.67 | 14.61 ± 4.08 | 9.10 ± 2.59 | 2.94 ± 1.40 |
P | 0.390 | 0.919 | 0.008 | <0.001 |
CACNA 1H | ||||
rs3794619 | ||||
TT | 25.35 ± 3.56 | 14.68 ± 4.55 | 10.36 ± 3.04 | 4.21 ± 1.03 |
TC + CC | 25.43 ± 3.47 | 14.60 ± 3.88 | 8.95 ± 2.58 | 2.67 ± 1.37 |
P | 0.897 | 0.920 | 0.009 | <0.001 |
rs7191246 | ||||
GG | 25.39 ± 3.46 | 14.66 ± 4.54 | 10.19 ± 2.93 | 4.06 ± 1.18 |
GC + CC | 25.31 ± 3.77 | 14.65 ± 3.65 | 8.95 ± 2.97 | 2.54 ± 1.27 |
P | 0.901 | 0.991 | 0.039 | <0.001 |