Table 2. Correlation of E2Fs’ genes expression with OS in GC patients with HER2 expression status.

E2Fs	HER2 status	Cases	Low	High	HR (95% CI)	P-value
E2F1	Negative	532	292	240	1.98 (1.58−2.48)	1.7e−09*
	Positive	344	131	213	1.93 (1.46−2.55)	2.7e−06*
E2F2	Negative	429	222	207	0.6 (0.46−0.79)	0.00018*
	Positive	202	115	87	0.6 (0.4−0.88)	0.0083*
E2F3	Negative	532	361	171	1.64 (1.3−2.07)	2.1e−05*
	Positive	344	185	159	1.76 (1.36−2.29)	1.6e−05*
E2F4	Negative	532	292	240	1.84 (1.47−2.3)	8.1e−08*
	Positive	344	120	224	2.01 (1.49−2.7)	2.5e−06*
E2F5	Negative	532	192	340	0.58 (0.46−0.72)	1.5e−06*
	Positive	344	126	218	0.71 (0.55−0.93)	0.011*
E2F6	Negative	532	201	331	0.69 (0.55−0.86)	0.0012*
	Positive	344	156	188	0.89 (0.68−1.15)	0.36
E2F7	Negative	429	154	275	0.54 (0.41−0.7)	3.7e−06*
	Positive	202	142	60	0.65 (0.43−1.01)	0.051

^*P<0.05.