Table 4. Correlation of E2Fs’ genes expression with OS in GC patients with gender expression status.
E2Fs | Gender | Cases | HR (95% CI) | P-value |
---|---|---|---|---|
E2F1 | Male | 545 | 2.33 (1.84−2.95) | 5.1e−13* |
Female | 876 | 2 (1.69−2.38) | 7.8e−16* | |
E2F2 | Male | 349 | 0.53 (0.39−0.72) | 2.6e−05* |
Female | 187 | 0.53 (0.31−0.91) | 0.02* | |
E2F3 | Male | 545 | 2.08 (1.68−2.58) | 9e−12* |
Female | 236 | 1.54 (1.05−2.25) | 0.026 | |
E2F4 | Male | 545 | 2.24 (1.79−2.81) | 7.2e−13* |
Female | 236 | 2.17 (1.53−3.09) | 8.6e−06* | |
E2F5 | Male | 545 | 0.65 (0.52−0.81) | 9e−05* |
Female | 236 | 0.59 (0.42−0.84) | 0.003* | |
E2F6 | Male | 545 | 0.89 (0.71−1.11) | 0.28 |
Female | 236 | 0.56 (0.39−0.79) | 0.00097* | |
E2F7 | Male | 349 | 0.6 (0.45−0.82) | 0.0011* |
Female | 187 | 0.48 (0.3−0.75) | 0.0011* |
P<0.05.