Table 1.

Evidence-based psychiatric rehabilitation interventions for SMI.

Evidence-based intervention	Main outcomes
Assertive community treatment	Decrease in length hospitalization and homelessness rates
Illness self-management training	Skills improvement to cope with the illness, relapses reduction and social functioning improvement
Cognitive behavioral therapy for psychosis	Positive and negative symptoms reduction, mood and social functioning improvement
Family interventions/psychoeducation	Relapses reduction, social functioning improvement, increase in treatment adherence, illness knowledge, family coping and decrease in family burden
Social skills training	Negative symptoms reduction, social skills and social functioning improvement
Cognitive remediation, including social cognitive and metacognitive training	Negative symptoms reduction, cognitive, social cognitive, metacognitive and psychosocial functioning improvement
Supported employment	Improvement in employment rates, hours worked and QoL
Physical aerobic exercise, including healthy lifestyle intervention	Positive and negative symptoms reduction, mood, cognition, QoL and social functioning improvement
Integrated early intervention for psychosis	Positive and negative symptoms reduction, treatment adherence, QoL, and social functioning improvement
Integrated intervention for comorbidity with SUD	Decrease in substance use and detention, improvement in social functioning
Psychoeducation for bipolar disorder	Decrease in illness recurrence, length and rates of hospitalization, increase in illness knowledge and treatment adherence, decrease in caregiver burden
Functional remediation for bipolar disorder	Cognitive and psychosocial functioning improvement
Dialectical behavior therapy—skills training groups—for BPD	Reduction in anger, suicidal and self-injurious behaviors

BPD, borderline personality disorder; QoL, quality of life; SMI, severe mental illness; SUD, substance use disorder.