Table 1.

Medications for treating dementia with Lewy bodies

Core feature	Drug class	Drug (generic)	Sample size (n)	References
Dementia	Cholinesterase inhibitor	Rivastigmine	120	[30]
		Galantamine	50	[31]
		Donepezil	140	[33]
	NMDA receptor antagonist	Memantine	72	[36]
			199	[37]
Hallucinations	Cholinesterase inhibitor	Rivastigmine	120	[30]
		Galantamine	50	[31]
		Donepezil	140	[33]
	Atypical antipsychotic (dopamine antagonist)	Quetiapine	40	[40]
	Novel antipsychotic (5-HT2A inverse agonist)	Pimavanserin	–	[41]
Parkinsonism	Dopamine precursor	Levodopa	–	[5, 38, 42]
	Anticonvulsant	Zonisamide	158	[43]
Fluctuations and agitation	Atypical antipsychotic (dopamine antagonist)	Quetiapine	–	[38, 40]
	Anticonvulsant	Valproic acid, divalproex	–	[50, 52, 53]
REM sleep behavior disorder	Benzodiazepine	Clonazepam	–	[54, 59]
	Hormone	Melatonin	110	[60]
			14	[61]

5-HT 5-hydroxytryptophan, NMDA N-methyl-d-aspartate, REM rapid eye movement