Table 1.
McArdle mice colony breeding results between 2013 and 2018. Abbreviations. (M): Males; (F): Females; N.A: Not applicable.
| Breedings (2013–2018) | ||||||||
|---|---|---|---|---|---|---|---|---|
| WT x HTZ | HTZ x HTZ | McA x HTZ | McA x McA | Statistics | Total | |||
| WT (M) x HTZ (F) | HTZ (M) x WT (F) | HTZ (M) x HTZ (F) | McA (M) x HTZ (F) | HTZ (M) x McA (F) | McA (M) x McA (F) | |||
| Total number of breedings | 9 | 10 | 47 | 58 | 6 | 9 | N.A | 139 |
| Total number of litters | 17 | 41 | 273 | 179 | 43 | 30 | N.A | 583 |
| Total number of mice | 103 | 189 | 1149 | 617 | 130 | 39 | N.A | 2227 |
| Total number of males | 45 | 102 | 578 | 325 | 64 | 19 | N.A | 1133 |
| % of males | 43,7 | 54,0 | 50,3 | 52,7 | 49,2 | 48,7 | N.A | 50,9 |
| Total number of females | 58 | 87 | 571 | 292 | 66 | 20 | N.A | 1094 |
| % of females | 56,3 | 46,0 | 49,7 | 47,3 | 50,8 | 51,3 | N.A | 49,1 |
| Mice/litter | 6,06 (±3,75) | 4,61 (±3,69) | 4,21 (±3,33) | 3,45 (±2,75) | 3,02 (±2,15) | 1,30 (±1,74) | p < 0.0001 | 3,77 (±1,61) |
| 5,03 (±3,73) | 4,21 (±3,33) | 3,36 (±2,64) | 1,30 (±1,74) | |||||
| Nº litters with 100% mortality | 3 | 13 | 61 | 48 | 7 | 14 | N.A | 146 |
| % litters with 100% mortality | 5,5 | 22,3 | 24,8 | 35,9 | N.A | 22,1 | ||
To calculate the statistical significance of the number of mice per litter the One-Way ANOVA with post-hoc Tukey Honestly Significant Difference (HSD) test was applied.