Table 2.
McArdle mice colony genotyping results between 2013 and 2018. Abbreviations.
| Breedings | Post-weaning genotyping | Embryo genotyping | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT x HTZ | HTZ x HTZ | HTZ x McA | HTZ x HTZ | |||||||||
| Offsprings | WT | HTZ | McA | WT | HTZ | McA | WT | HTZ | McA | WT | HTZ | McA |
| Nº mice per genotype | 96 | 137 | N.A | 368 | 718 | 67 | N.A | 580 | 122 | 12 | 17 | 9 |
| Genotype % | 41.2 | 58.8 | N.A | 31.9 | 62.3 | 5.8 | N.A | 82.6 | 17.4 | 31.5 | 44.7 | 23.6 |
| Expected Genotype % | 50 | 50 | N.A | 25 | 50 | 25 | N.A | 50 | 50 | 25 | 50 | 25 |
| Statistics | Fisher’s test p = 0.035 | Chi-square test p < 0.001 | Fisher’s test p < 0.001 | Chi-square test p = 0.864 | ||||||||
N.A: Not applicable. To compare obtained versus expected mouse genotypes Fisher’s exact test (two-group comparisons, i.e., WT x HTZ and HTZ x McA breedings) and Chi-square test (three-group comparisons, i.e., HTZ x HTZ breedings) were used.